Descriptions of identified polypeptide targets, enzymes, carriers, or transporters.

Polypeptides_Carrier_Drug

Polypeptides_Enzyme_Drug

Polypeptide_Target_Drug

Polypeptides_Transporter_Drug

Format

a tibble with 20 variables:

id

Universal Protein Resource (UniProt) identifier

source

Specifies whether the identified polypeptide ID is associated with any of the following UniProt knowledge bases: Swiss-Prot, which is manually annotated and reviewed, or TrEMBL, which is automatically annotated and not reviewed.

name
general_function

General summary of the physiological function of the polypeptide

specific_function

A more specific description of the polypeptide’s physiological function within the cell.

gene_name

The short name commonly associated with the associated gene. Eg. PTGS1.

locus

The specific chromosomal location or position of the gene’s sequence on a chromosome.

cellular_location

The cellular location of the polypeptide.

transmembrane_regions

Areas of the polypeptide sequence that span a biological membrane.

signal_regions

Location of any signal peptides within the polypeptide sequence.

theoretical_pi

Theoretical isoelectric point.

molecular_weight

The molecular weight of the polypeptide.

chromosome_location

The chromosomal location of the polypeptide gene

organism

The organism in which this polypeptide functions.

organism_ncbi_taxonomy_id
amino_acid_sequence

The amino acid sequence of the polypeptide

amino_acid_format
gene_sequence

The sequence of the associated gene.

gene_format
parent_key

drugbank id

An object of class spec_tbl_df (inherits from tbl_df, tbl, data.frame) with 3 rows and 20 columns.

An object of class spec_tbl_df (inherits from tbl_df, tbl, data.frame) with 35 rows and 20 columns.

An object of class spec_tbl_df (inherits from tbl_df, tbl, data.frame) with 50 rows and 20 columns.

An object of class spec_tbl_df (inherits from tbl_df, tbl, data.frame) with 17 rows and 20 columns.

Details

Each target, enzyme, carrier and transporter elements may include one or more polypeptide.